Mechanisms of Recovery From Type 2 Diabetes After Malabsorptive Bariatric Surgery

Mechanisms of recovery from type 2 diabetes after malabsorptive bariatric surgery.

Currently, there are no data in the literature regarding the pathophysiological mechanisms involved in the rapid resolution of type 2 diabetes after bariatric surgery, which was reported as an additional benefit of the surgical treatment for morbid obesity. With this question in mind, insulin sensitivity, using euglycemic-hyperinsulinemic clamp, and insulin secretion, by the C-peptide deconvolu...

Remission of type 2 diabetes after bariatric surgery.

Mechanisms of early improvement/resolution of type 2 diabetes after bariatric surgery.

Bariatric surgery represents the main option for obtaining substantial and long-term weight loss in morbidly obese subjects. In addition, malabsorptive (biliopancreatic diversion, BPD) and restrictive (roux-en-Y gastric bypass, RYGB) surgery, originally devised to treat obesity, has also been shown to help diabetes. Indeed, type 2 diabetes is improved or even reversed soon after these operation...

Metabolic Mechanisms in Obesity and Type 2 Diabetes: Insights from Bariatric/Metabolic Surgery

Obesity and the related diabetes epidemics represent a real concern worldwide. Bariatric/metabolic surgery emerged in last years as a valuable therapeutic option for obesity and related diseases, including type 2 diabetes mellitus (T2DM). The complicated network of mechanisms involved in obesity and T2DM have not completely defined yet. There is still a debate on which would be the first metabo...

Diabetes remission after bariatric surgery: which are the mechanisms?

Bariatric surgery is being performed increasingly in response to the epidemic of obesity plaguing the Western society. The numbers of such procedures have increased sharply worldwide, with the Roux-en-Y gastric bypass (GBP) currently being considered as the gold-standard operative treatment for morbid obesity. Its widespread acceptance lies in part in its remarkable success in reducing weight o...